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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11966 | MCHR1 antagonist 2 | HER , Melanin-concentrating Hormone Receptor (MCHR) | |
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG. | |||
TP1996 | MCH(human, mouse, rat) | MCH (human, mouse, rat) | GPR , Melanin-concentrating Hormone Receptor (MCHR) |
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increase... | |||
T8004 | SNAP 94847 hydrochloride | GPR , Melanin-concentrating Hormone Receptor (MCHR) | |
SNAP 94847 hydrochloride is a melanin-concentrating hormonereceptor1 (MCHR1) antagonist(Ki= 2.2 nM) | |||
T5406 | SNAP 94847 | SNAP-94847 | GPR , Melanin-concentrating Hormone Receptor (MCHR) |
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice. | |||
T16852 | SB-568849 | Others | |
SB-568849 is a melanin-concentrating hormone receptor 1 antagonist (pKi: 7.7). | |||
T26677 | ATC0175 | ATC 0175,ATC-0175 | |
ATC0175 is a melanin-concentrating hormone receptor 1 antagonist with oral activity. | |||
T26676 | ATC0065 | ATC 0065,ATC-0065 | |
ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity. | |||
T26703 | AZ13483342 | AZ-13483342,AZ 13483342 | |
AZ13483342 is an antagonist of the melanin concentrating hormone receptor 1 (MCH1) with a potential diabetes therapeutic activity. | |||
T14372 | AZD1979 | Others | |
AZD1979 is an antagonist of Melanin-concentrating hormone receptor 1 (MCHr1) (IC50: 12 nM). | |||
T28902 | T-226296 | T 226296,T226296 | |
T-226296 is a antagonist of melanin concentrating hormone receptor 1 (MCHR1). | |||
T16293 | NGD-4715 | Others | |
NGD-4715 is a selective and orally active antagonist of melanin-concentrating hormone receptor 1. | |||
T10173 | MCHR1 antagonist 1 | Others | |
MCHR1 antagonist 1 is a selective antagonist of melanin-concentrating hormone-1 (MCH1) receptor (Kb: 1 nM, Ki: 4 nM at human MCH1). | |||
T23719 | AMG-076 | ||
AMG-076 is an antagonist of melanin-concentrating hormone receptor 1. It also reduced hERG inhibition. | |||
T69170 | ATC0065 HCl | ||
ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist. | |||
T11965 | MCHR1 antagonist 3 | Others | |
MCHR1 antagonist 3, a potent antagonist of the melanin-concentrating hormone receptor-1 (MCHR1), is employed for the regulation of energy metabolism. | |||
T15450 | GW-803430 | GW-3430 | Others |
GW-803430 is a potent and selective antagonist of melanin-concentrating hormone receptor 1 (MCH R1) (pIC50: 9.3). GW-803430 is orally active in an animal model of obesity. | |||
T7749 | ALB-127158 | ||
ALB-127158(a) is a potent and selective melanin concentrating hormone 1 ( MCH 1 ) receptor antagonist which may be a potential treatment for inflammatory bowel disease (IBD). | |||
T76640 | HMCH-1R antagonist 1 | ||
HMCH-1R Antagonist 1 (Compound 30) serves as an effective and selective antagonist for the human melanin-concentrating hormone receptor 1 (hMCHR1), exhibiting a K_B value of 3.6 nM. It possesses the ability to bind to hM... |